The authors review evidence of gender-responsive factors for women in prisons. Some gender-responsive needs function as risk factors in prison settings and contribute to women’s maladjustment to prison; guided by these findings, the authors outline ways in which prison management, staff members, and programming can better serve female prisoners by being more gender informed. The authors suggest that prisons provide treatment and programming services aimed at reducing women’s criminogenic need factors, use gendered assessments to place women into appropriate interventions and to appropriately plan for women’s successful reentry into the community, and train staff members to be gender responsive.