What is already known about this topic?
The COVID-19 pandemic caused approximately 375,000 deaths in the United States during 2020.
What is added by this report?
The age-adjusted death rate increased by 15.9% in 2020. Overall death rates were highest among non-Hispanic Black persons and non-Hispanic American Indian or Alaska Native persons. COVID-19 was the third leading cause of death, and the COVID-19 death rate was highest among start highlightnon-Hispanic American Indian or Alaska Native personsend highlight.
What are the implications for public health practice?