What is already known about this topic?
The COVID-19 pandemic caused approximately 375,000 deaths in the United States during 2020.
What is added by this report?
The age-adjusted death rate increased by 15.9% in 2020. Overall death rates were highest among non-Hispanic Black persons and non-Hispanic American Indian or Alaska Native persons. COVID-19 was the third leading cause of death, and the COVID-19 death rate was highest among start highlightnon-Hispanic American Indian or Alaska Native personsend highlight.
What are the implications for public health practice?
Provisional death estimates provide an early indication of shifts in mortality trends. Timely and actionable data can guide public health policies and interventions for populations experiencing higher numbers of deaths that are directly or indirectly associated with the COVID-19 pandemic.